Duloxetine was approved for the treatment of major depression in 2004. While duloxetine has demonstrated improvement in depression-related symptoms compared to placebo, comparisons of duloxetine to other antidepressant medications have been less successful. A 2012 Cochrane Review did not find greater efficacy of duloxetine compared to SSRIs and newer antidepressants. Additionally, the review found evidence that duloxetine has increased side effects and reduced tolerability compared to other antidepressants. It thus did not recommend duloxetine as a first line treatment for major depressive disorder, given the (then) high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy. do not list duloxetine among the recommended treatment options. A review from the Annals of Internal Medicine lists duloxetine among the first line drug treatments, however, along with citalopram, escitalopram, sertraline, paroxetine, and venlafaxine. In some cases, they may not be available in all strengths or forms as the brand-name drug. Duloxetine oral capsule is available as the brand-name drugs Cymbalta and Irenka. Generic drugs usually cost less than the brand-name version. Duloxetine oral capsule is used to treat: Duloxetine belongs to a class of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs). It works by balancing chemicals in your brain that cause depression and anxiety. By balancing these chemicals, this drug also helps inhibit pain signals from your nerves to your brain. Duloxetine oral capsule can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You shouldn’t drive, use heavy machinery, or do other dangerous activities until you know how it affects you. In adults, the more common side effects of duloxetine can include: Call your doctor right away if you have serious side effects. Buy clomid online fast shipping Metformin kidney stones Prednisone while breastfeeding I have taken both 60mg & 120mg Duloxetine without any apparent side effects. It did not help at all with my peripheral neuropathy though. The dose is normally 30 - 60mg daily for nerve pain problems & there's no evidence that over 60 mg helps, but in desparation we tried anyway. Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor SNRI antidepressants used for treating depression, anxiety disorder, and pain. Other drugs in this class include milnacipran, venlafaxine, and desvenlafaxine. Mg/day PO initially in single daily dose or divided q12hr for 1 week if patient needs to adjust to therapy. The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs and SSRIs, including duloxetine, when administered concomitantly with other serotonergic drugs including triptans, tricyclic. Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. Duloxetine is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old. Duloxetine is also used in adults to treat fibromyalgia (a chronic pain disorder), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain). Duloxetine is also used to treat pain caused by nerve damage in adults with diabetes (diabetic neuropathy). Do not take duloxetine within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Report any new or worsening symptoms to your doctor. Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. Show More Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine mg Duloxetine in the treatment of generalized anxiety disorder, Duloxetine Cymbalta, Antidepressant, Side Effects, Dosing, Uses Can zoloft cause insomniaHow to get cheap viagraViagra developmentMetoprolol low heart rate Cymbalta is available in 20 mg, 30 mg, and 60 mg strengths, allowing your health care provider to taper the dose slowly. Consult your health care provider for specific recommendations on dosage. Cymbalta Duloxetine - Side Effects, Dosage, Interactions.. Cymbalta duloxetine dosing, indications, interactions.. Duloxetine Cymbalta Generic Approved but Caution Exists.. Jun 13, 2014 · DULOXETINE HYDROCHLORIDE 20 MG- duloxetine capsule, delayed release DULOXETINE HYDROCHLORIDE 30 MG- duloxetine capsule, delayed release DULOXETINE HYDROCHLORIDE 60 MG- duloxetine capsule, delayed release Number of versions 1 Duloxetine 30mg Capsules Unfortunately our full catalog may not be displayed in your state. If you contact our Customer Support by one of the methods below, we will be able to assist you in locating the product you are looking for. Duloxetine has good oral bioavailability, averaging 50% after one 60 mg dose. There is an average 2-hour lag until absorption begins with maximum plasma concentrations occurring about 6 hours post dose.