It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Corticosteroids plaquenil Methotrexate and folic acid and plaquenil for lupus Plaquenil and erosive osteoarthritis If the initiation of chemoprophylaxis is delayed ie, 2 weeks of therapy not completed prior to the exposure, the manufacturer recommends initiating therapy by doubling the initial dose 13 mg/kg of hydroxychloroquine sulfate and administering in 2 divided doses 6 hours apart; maximum single dose 400 mg/dose hydroxychloroquine sulfate. Hydroxychloroquine dosing information. Usual Adult Dose for Malaria Treatment of the acute attack 800 mg 620 mg base followed in 6 to 8 hours by 400 mg 310 mg base, then 400 mg 310 mg base once a day for 2 consecutive days; alternatively, a single dose of 800 mg 620 mg base has also been effective Sep 13, 2019 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine 400 mg od Wrong Hydroxychloroquine Dose Is Common, Putting Eyes at Risk - News, Hydroxychloroquine Uses, Dosage & Side Effects - Chloroquine chemistryPlaquenil and dental inplantsHydroxychloroquine patient info Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Plaquenil Side Effects Common, Severe, Long Term -. Hydroxychloroquine - Wikipedia. Adults—At first, 400 to 600 milligrams mg taken as a single dose or in two divided doses once a day. Then, 200 to 400 mg taken as a single dose or in two divided doses once a day. Your doctor may adjust your dose if needed. However, dose is usually not more than 600 mg or 6.5 mg per kilogram kg of body weight per day, whichever is lower. Symptoms of overdose. Drowsiness dry mouth increased thirst loss of appetite mood changes no pulse or blood pressure numbness or tingling in the hands, feet, or lips unconsciousness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity.