My worst symptoms so far have been raynauds, fatigue, telangiectasias , heart burn, and digital ulcers. I'm fortunate that my lungs have been unaffected up to this point but I'm worried that contracting the virus could cause fibrosis in the lungs and lead to ILD and PAH. What is the drug plaquenil used to treat What lab needs to be monitored for hydroxychloroquine Chloroquine toxicity eye Treatment of chloroquine resistant malaria in pregnancy Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. My wife has recently been diagnosed with CREST/scleroderma. Can anything be said about the overall life expectancy of people with this diagnosis? CREST syndrome, also known as limited scleroderma, is a widespread connective tissue disease characterized by changes in the skin, blood vessels, skeletal muscles, and internal organs. The symptoms involved in CREST syndrome are associated with the generalized form of the disease systemic sclerosis scleroderma. Anybody have any knowledge about this that they can share? I've been trying to do some research but haven't come up with any solid answers. Plaquenil crest syndrome CREST syndrome symptoms, treatments & forums PatientsLikeMe, Scleroderma Life Expectancy Johns Hopkins Arthritis Center Ask The. Chloroquine vs chloroquinine Hydroxychloroquine Plaquenil Fatigue, joint pain Mild mostly GI symptoms, except for serious eye problems with chronic use at high dosages Antimalarial drug, frequently used to treat lupus and rheumatoid arthritis. Limited research on specific effectiveness in scleroderma. Imatinib mesylate Gleevec Skin fibrosis, pulmonary Moderate Anti-cancer drug. Scleroderma Treatment General – Standard - Scleroderma.. CREST syndrome Genetic and Rare Diseases Information Center.. Just Diagnosed with Crest Syndrome & Prescribed Plaquenil.. For example, the CREST syndrome Calcinosis, Raynaud’s phenomenon, Esophageal dysmotility, Sclerodactyly, Telangeictasias falls into the traditional limited subtype; yet evidence suggests that survival is better in those with the CREST syndrome than an intermediate group of patients in the limited group who have skin changes extending onto the forearms 31. Nov 25, 2019 Usual Adult Dose for Rheumatoid Arthritis. -Initial dose 400 to 600 mg 310 to 465 mg base orally once a day to optimum response usually 4 to 12 weeks -Maintenance dose 200 to 400 mg 155 to 310 mg base orally once a day Dose adjustment The dose may need to be reduced temporarily if adverse side effects occur; Undifferentiated connective tissue disease UCTD is an autoimmune disease that can affect several systems in the body. Connective tissue disease CTD is classified as undifferentiated CTD when signs and symptoms are consistent with a CTD, but do not fulfill the diagnostic or classification criteria for one of the previously defined CTDs for example, rheumatoid arthritis or lupus.