While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "Hydrochloroquine (Plaquenil) has been a blessing for me. Chloroquine and filipin Chloroquine solubility in dmso Hydroxychloroquine solubility Chloroquine depensed to us troop in honduran Aug 26, 2016 Yes, plaquenil is difficult to adjust first, but after the first year of treatment and side effects, the benefits outweigh the problems. So, stick with it. In my opinion, the plaque nil is keeping the immune system regulated and the pain and other symptoms described will reduce. Lupus is not an illness without pain or sacrifice, but, it’s. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. My knees and legs hurt, back, hips, shoulders, fingers, and now my left heel - which has me limping half the time. I felt the Plaquenil helped the fatigue, but it seems the pain is sabotaging that effect. It also stopped my hair loss and soon after starting it, the skin on my face became more normal and less coarse. I was thrilled. I do occasionally experience dry eyes and a little scalp itch but asserting that it's caused by Hydrochloroquine would be anecdotal at best. It took about 5 weeks to take effect but my RA is basically a non factor now. Pain worse after plaquenil When starting hydroxychloroquine do symptoms feel. - LUPUS UK, Hydroxychloroquine Plaquenil Side Effects & Dosage for. Symptoms of hydroxychloroquine retinopathy I took plaquenil for about 5 years. Had bouts of bad gastro problems, but no flu symptoms. Had bouts of bad gastro problems, but no flu symptoms. But, it started to casue redness and horribly irritation on my scalp and spotty some large hair loss. Does anyone else feel worse on Plaquenil?. Plaquenil and muscle aches and pains?. The Risk of Retinal Toxicity with Plaquenil - Sjogren's. When starting hydroxychloroquine do symptoms feel worse. got so ill they wanted me to go on chemo based drugs but I did not want that either. so reluctantly went back on the plaquenil. imo its made me worse. I hate it and now cant come off it but cannot bear the fibrio type pain it has given me. now they want me on a drug they use for. In April of 2012 I started taking 400 mg 2 x's a day. I did start to notice that I was having pain when I tried to sleep at night. Mostly in my arms hands and ankles. Then I started to notice that I was having pain in my back and left hip as the day wore on and especially after taking the plaquenil in the evening. A lower dose may stop them. Do not lower the dose on your own. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem.