B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Hydroxychloroquine dosage for osteoarthritis Hydroxychloroquine hearing loss Plaquenil time to work A, Bluish-green pigmentation on the legs in a patient with systemic lupus erythematosus without lupus lesions at the time of the skin biopsy. B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. Rheumatoid arthritis RA mainly affects the joints. But it, and many of the medications that treat it, can also affect the you recognize any of these problems? Rheumatoid Nodules. About 1. Apr 15, 2016 Discolored patches on the skin are a common occurrence that most people will experience at some point in their lives. Skin discoloration can occur alongside other symptoms like itching, pain, and. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Skin discoloration plaquenil Montelukast skin rash, plaquenil and skin discoloration., Rheumatoid Arthritis Skin Problems Nodules, Rashes, and More Best time to take hydroxychloroquine Discoid lupus lesions are often red, scaly, and thick. Usually they do not hurt or itch. Over time, these lesions can produce scarring and skin discoloration darkly colored and/or lightly colored areas. Discoid lesions that occur on the scalp may cause the hair to fall out. If the lesions form scars when they heal, the hair loss may be permanent. How Lupus Affects The Skin Lupus Foundation of America. Discolored Skin Patches Pictures, Causes, and Treatments. Plaquenil Advanced Patient Information -. Sulfasalazine may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine Skin discoloration - bluish in Plaquenil - how severe and when it was recovered? Summary We study how severe was Skin discoloration - bluish, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil. Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong.