Suddenly I'm experiencing eye problems (blilnd spots). I have stopped taking plaquenil, but now I'm being told by doctors that the damage is not necessarily reversible especially if you have taken it for a long time. How to get on hydroxychloroquine Chloroquine synthesis mechanism Although it is considered rare, retinal toxicity from the intake of Plaquenil can be irreversible even if the drug is discontinued 2, 3. What is Plaquenil Toxicity? The toxicity resulting from the intake of Plaquenil is due to its affinity for melanin-containing structures in the body. Retinal Scanning Laser — Macula. To gather the clinical information required to screen for early detection of plaquenil-induced toxic maculopathy, emphasis is placed on spectral domain OCT testing, particularly ganglion cell analysis. Parafoveal thinning may be seen on the macular thickness map imaged with Cirrus OCT Is Damage Still Occurring? Can Plaquenil macular toxicity continue to progress long after the patient stops taking the drug. and foveal thickness measurements served as the standard metrics on SD-OCT testing. Sfikakis PP, Mavrikakis E, et al. The incidence of irreversible retinal toxicity in patients treated with hydroxychloroquine a. My mother was diagnosed with Plaquenil Toxicity in 2007 she first noticed changes in 2006, although being followed by her eye doctor they failed to notice this as Plaquenil TX until it was to late. I'm hoping to find people who have recovered from the eye damage. Retinal thickness map plaquenil toxicity Plaquenil Retinotoxicity Updated Guidelines, H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS Plaquenil no period Aug 06, 2014 Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Multimodal Imaging in Plaquenil Toxicity. Is Damage Still Occurring? - Review of Optometry. Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS. Hydroxychloroquine Retinopathy - Insensitivity of Retinal Nerve Fiber Layer Thickness Measurements as a Screening Test Hydroxychloroquine Retinopathy - Misinterpretation of VIsual Fields, Part D Hydroxychloroquine Retinopathy - Misinterpretation of VIsual Fields, Part F Retinal toxicity has been shown in patients taking greater than 3 mg/kg/day of chloroquine or 6.5 mg/kg/day of hydroxychloroquine. While most cases of toxicity have been reported for chloroquine, hydroxychloroquine has supplanted it as the more commonly used treatment agent for both RA and SLE. 2 Plaquenil Toxicity - Bulls Eye Maculopathy 878 views 70-year-old woman with systemic Lupus erythematosus and clotting problems. She was on the Plaquenil for about eight years and then off the Plaquenil for the last eight years because she developed macular toxicity.