It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Return of chloroquine antimalarial efficacy in malawi Mefloquine or plaquenil Drugs that inhibit CYP3A4 enzymes may increase plasma levels of hydroxychloroquine. Proton pump inhibitors may antagonize the immunomodulating effects of hydroxychloroquine. 7. Additional known interactions between hydroxychloroquine and coadministered drugs may be described in the FDA-approved Full Prescribing Information for Plaquenil. 9. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine and chloroquine are antimalarial drugs commonly used for the treatment of rheumatic diseases. Multiple mechanisms might explain the efficacy and adverse effects of these drugs. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine and reduction of metastasis Clinical Trials Using Hydroxychloroquine - National Cancer., Hydroxychloroquine Plaquenil Side Effects & Dosage for. Plaquenil retinopathy info for patient rheumatolBulleye chloroquin retinopathyRetinal toxicity hydroxychloroquineHydroxychloroquine sulphate and pregnancy This phase I trial studies the best dose of hydroxychloroquine when given together with binimetinib in treating patients with KRAS gene mutated pancreatic cancer that has spread to other places in the body metastatic. Binimetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Clinical Trials Using Hydroxychloroquine - National Cancer Institute. Mechanisms of action of hydroxychloroquine and chloroquine.. Hydroxychloroquine Plaquenil. Detailed Hydroxychloroquine dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria Prophylaxis and more; plus renal, liver and dialysis adjustments. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Hi, A month ago my reumy told me to stop my 200mg of hydroxy as I was still getting flares in my joints! Which sempt strange to me but within 3 week I was in agony, struggling to even walk to the bathroom first thing in a morning with painful knee/ankle joints, fingers and wrists were agony.