Alternatively, we suggest using this opportunity to take a little break from work and read some of the interesting articles below. Summary Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Hydroxychloroquine and hashimoto's disease Hydroxychloroquine to treat hair loss Plaquenil usage and autism Does plaquenil show up in the blood Regulators for cancer chemotherapy. We investigated the potential roles and mechanisms of hydroxychloroquine HCQ in combination with chemotherapy in lung cancer treatment. Methods The effects of combined treatment on non-small cell lung cancer NSCLC were investigated using cell viability assays and animal models. To assess the synergistic actions of lidamycin LDM and chloroquine CQ, a lysosomal enzyme inhibitor, in human non-small cell lung cancer NSCLC cells, and to elucidate the potential mechanisms. Chloroquine is a potent blocker of autophagy and has been demonstrated in a lab setting to dramatically enhance tumor response to radiotherapy, chemotherapy and even anti-hormonal therapy. Thus, chloroquine might very well be able to increase overall survival in small cell lung cancer by sensitizing cells resistant to chemotherapy and radiotherapy. It is one of very few available drugs that inhibits autophagy, a mechanism associated with its anticancer properties. Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. Chloroquine lung cancer A Vision of Cancer From an Ayurvedic Perspective - Vaidya., Chloroquine potentiates the anti-cancer effect of lidamycin. How long for chloroquine to work malariaCellcept and plaquenilPlaquenil pap frequencyWhat is another name for hydroxychloroquine The most common type of lung cancer is adenocarcinoma ADC, comprising around 40% of all lung cancer cases. In spite of achievements in understanding the pathogenesis of this disease and the. Cell death-based treatment of lung adenocarcinoma Cell.. Chloroquine as an Anti-Autophagy Drug in Stage IV Small Cell.. Chloroquine inhibits cell growth in human A549 lung cancer.. Autophagy and cancer. A large body of evidence suggests that the relationship between autophagy and cancer is complex.42, 43 On the one hand, autophagy appears to inhibit malignant transformation, reflecting its capability to limit the accumulation of potentially oncogenic entities like depolarized mitochondria which overproduce potentially genotoxic reactive oxygen species, ROS. Aug 11, 2014 The anti-cancer effect of the antimalarial agent chloroquine when combined with conventional chemotherapy has been well documented. To date, it was assumed that chloroquine increases the. Chloroquine, a drug that has historically been used to treat malaria, has recently been combined with a new drug, Tarceva, which kills lung cancer cells. Tarceva only works for some patients, and the cancer almost always becomes resistant after prolonged exposure to the drug.