What is the half life of plaquenil

Discussion in 'Canadian Pharmacies Online' started by Badsky, 21-Feb-2020.

  1. Le secret XenForo Moderator

    What is the half life of plaquenil


    Hi Dr V, I am at a crossroad of considering to go back on Plaquenil . A year ago I proposed to go off Plaquenil after being on it for 22 years.

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    Plaquenil pla´kwĕ-nil trademark for a preparation of hydroxychloroquine, an antiinflammatory and antiprotozoal agent used for treatment of malaria, lupus erythematosus, rheumatoid arthritis, and giardiasis. With a half-life of 537 hours 22.4 days. In the same study, the plasma peak concentration was. 50.3 ng/mL reached in 3.74 hours with a half-life of 2963 hours 123.5 days. Urine hydroxychloroquine levels were still detectable after 3 months with approximately 10% of the dose excreted as the parent drug. The one thing that concerns me about the Plaquenil is the half life is about 50 days. So, after even just a couple weeks on it.would take you many months for it to leave your system. Also, you should get a baseline eye test before or shortly after starting the Plaquenil. And, then yearly exams after that to check for Retinopathy.

    If I had joint or muscle aches, I took care of it by resting, Aleve and ice. At my recent eye exam the doctor mentioned I had reached the plaquenil toxicity level and that my retina cells could die (which do not regenerate! My proposal was based on the fact that I had not had any major inflamation that completely shut me down or keep me from being active.

    What is the half life of plaquenil

    Plaquenil hydroxychloroquine sulfate dosing, indications., PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION

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  7. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

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    Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The absorption half-life was approximately 3 to 4 hours and the terminal half-life ranged from 40 to 50 days. The long half-life can be attributed to extensive tissue uptake rather than through decreased excretion. Peak plasma levels of hydroxychloroquine were seen in about 3 to 4 hours. It is now 6 weeks later, I've titrated up to 600mg. per day, and I am SEVERELY depressed, to the point I can't get out of bed some days. I am sicker mentally than I have been for 16 years, and it didn't start until I started the plaquenil. I'm so anxious, I'm agoraphobic and having anger attacks. I have never been agoraphobic in my life.

     
  8. Vodoley New Member

    Download PDF Many systemic medications may cause retinal toxicity. Hydroxychloroquine Side Effects, Dosage, Uses, and More Blindness From Plaquenil - Scleroderma - Inspire Hydroxychloroquine toxicity - EyeWiki
     
  9. Artad New Member

    Sjogren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. Lupus Medications and Treatments I am so afraid to take plaquenil for lupus treatment! any. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus
     
  10. Moschino Well-Known Member

    Plaquenil and Fibromyalgia - Sjogren's World Hello learned friends! For those of you with Fibromyalgia.you been prescribed Plaquenil? And was it effective? I have a dear friend who suffers from a lot of pain and fatigue from his Fibro, and he asked me if he should speak with his doc about it?

    Fibromyalgia Creating a Treatment Plan