Chloroquine poisoning antidote

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    Chloroquine poisoning antidote

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    OVERDOSAGE. Single oral doses of metronidazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Poisoning, deliberate or accidental, with drugs used to treat malaria, seems to be uncommon although data is not available from South Sudan. A study in Uganda suggested around 3% of all cases of poisoning admitted to hospital had taken chloroquine no other anti-malarial drugs were involved 1. Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ.

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    Chloroquine poisoning antidote

    Chloroquine - wikitox, Poisoning by anti-malarial drugs - SSMJ

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  5. Nova Scotia Provincial Antidote Kit Manual. IWK Regional Poison Centre 1.800.565.8161 updated 05/2015. Poison & Antidote Chart. Note This document pertains only to the antidotes contained in the antidote kit. Many other antidotes exist if information is required, contact the poison centre at 1-800-565-8161

    • Poison & Antidote Chart IWK Regional Poison Centre.
    • Chloroquine and Hydroxychloroquine Toxicity Treatment..
    • Treatment of hydroxychloroquine overdose - ScienceDirect.

    Overdose. Chloroquine is very dangerous in overdose. It is rapidly absorbed from the gut. In 1961, published studies showed three children who took overdoses died within 2.5 hours of taking the drug. While the amount of the overdose was not cited, the therapeutic index for chloroquine is known to be small. CONCLUSIONS The mortality rate in patients with acute chloroquine poisoning, including those patients sick enough to be referred to a specialty unit such as ours, can be limited to or = 10%. This finding appears to be true even in patients with massive ingestions. Hydroxychloroquine – which has a similar toxicity profile – has largely superseded it for the treatment of rheumatoid arthritis. In overdose both chloroquine and hydroxychloroquine cause sodium channel blockade with primarily cardiovascular and central nervous system effects, as well as hypokalemia due to intracellular potassium shifts.

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    This is not a list of all drugs or health problems that interact with hydroxychloroquine. What are the side effects of using hydroxychloroquine. Exacerbation of Psoriasis due to Hydroxychloroquine What are the side effects of hydroxychloroquine and.
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