It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Médicament mylan-hydroxychloroquine Dosage of chloroquin forvivax malaria Hi -. I just started Plaquenil 400 mg a day two week ago and I started feeling less achy and tired a few days ago. Is it possible for it to work quicker in some people? I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Last week my doc added plaquenil to the mix. I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. I suggest you ask your rhuemie for additional help in the meantime. I have had RA going on 12 years, and originally way back when I ws given plaquenil alone and it did nothing. I started on Plaquenil in 2015 200 mg then increased to 400 mg after 3 months. It took many months for the ulcer like spots to go away but the drug works. In January 2018, I no longer had insurance so I dropped back down to 200 mg. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Did plaquenil work for you Plaquenil Uses, Dosage & Side Effects -, How long did Plaquenil/Hydroxychloroquine take? DailyStrength Chloroquin urine colorCan i take plaquenil and lisinopril together Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil Drug and Medication User Reviews on RxList. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Do not use Plaquenil without telling your doctor if you are breast-feeding. Our blog on Lupus and Pregnancy has much more valuable information on this topic. Back to top. We hope that this blog has been helpful in answering some of your questions about Plaquenil and other antimalarial drugs used to treat lupus. Jun 30, 2015 Tell your doctor if you are breastfeeding or plan to breastfeed. Plaquenil has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from Plaquenil, a choice should be made whether to stop nursing or to stop use of this medication. User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners.