It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Hydroxychloroquine pn singlecare Plaquenil and drinking alcohol Aralen side effects and instructions It can reduce skin problems in lupus and prevent swelling/pain in arthritis. How to use Plaquenil. This medication is not recommended for long-term use in children. If a child accidentally. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Long term use of plaquenil for lupus Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Hydroxychloroquine with lamotrigine with oxycodonePlaquenil fact sheet Safety of Long term use of Hydroxychloroquine Therapy Further Verified for People with Lupus Hydroxychloroquine Plaquenil® was approved by the Food and Drug Administration for symptoms of lupus. The greatest concern people with lupus have when taking hydroxychloroquine is related to vision and an increase in risk for retinal damage. Safety of Long term use of Hydroxychloroquine Therapy Further Verified.. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil. For some people with very mild lupus, NSAIDs alone are enough to control symptoms. Antimalarial drugs. Hydroxychloroquine Plaquenil is used to treat malaria, and researchers have found that this drug also helps with lupus flares. These drugs work well with mild to moderate cases of lupus. This medication is also used, usually with other medications, to treat certain auto-immune diseases lupus, rheumatoid arthritis when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs DMARDs. Long-Term Additive Cardiovascular Benefit of Plaquenil and Aspirin in Lupus. Systemic lupus erythematosus SLE is associated with an increased risk of cardiovascular disease CVD. The cardioprotective benefits of aspirin ASA are well known and the ancillary CV and diabetogenic effects of hydroxychloroquine HCQ have also been shown.