Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine proguanil malaria prophylaxis Can methrotrexate be taken with plaquenile Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia. Jun 11, 2013 I was diagnosed with UCTD at first but rheumy is starting to believe that it's primary sjogrens. My joint pain is under control and mild at times. The fatigue almost gone! However rheumy says plaquenil does not target the specific symptoms of dry eyes and dry mouth. She is right. I treat my dry eyes with restasis drops and the dry mouth comes. Aug 29, 2014 In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias joint pain, dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil causing dry mouth What does plaquenil DO? My doctor wants to put me on it but I., Study Raises Questions about Sjogren's and Plaquenil Hydroxychloroquine for hair lossChloroquine for malariaPlaquenil se puede mezclar con ibuprofen Many people with lupus will experience symptoms such as dry eyes and/or a dry mouth. These symptoms are most commonly caused by Sjögren’s pronounced show-gren’s syndrome, an autoimmune disease that causes inflammation and damage to the glands that produce moisture. About one-third of people with SLE have secondary Sjögren’s syndrome. Coping with Dry Eyes and Dry Mouth - LUPUS UK. The Risk of Retinal Toxicity with Plaquenil - Sjogren's. Plaquenil hydroxychloroquine sulfate Drug / Medicine.. Sjogren's Syndrome is a common cause of Dry Mouth. It is a disorder of the autoimmune system which destroys the glands which produce tears and saliva. This is what causes Dry Mouth for people with this disorder. The condition may affect other parts of the body, including the kidneys and lungs. Symptoms of overdose. Drowsiness; dry mouth; increased thirst; loss of appetite; mood changes; no pulse or blood pressure; numbness or tingling in the hands, feet, or lips; unconsciousness; Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Feb 16, 2016 Lupus can cause dry mouth leading to tooth issues. And often Lupus is accompanied by a secondary disorder, Sjogren's Syndrome, which also causes dry mouth leading to tooth decay. I don't think the Plaquenil or the Prednisone are causing the issue -- you should check in with your rheumatologist.