Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil dosage for osteoarthritis Symptoms of hydroxychloroquine retinopathy Highly effective in the treatment of amebic liver abscess when administered with emetine or dehydroemetine. Like emetine and dehydroemetine, it is not effective against luminal forms. Irreversible retinal damage does not occur with the dose and duration used for the treatment of hepatic amebiasis. Q. 5 All are used in treatment of amoebic liver abscess except - A Diloxanide furoate B Chloroquine C Metronidazole D Emetine Q. 5 All are used in treatment of amoebic liver abscess except - A Diloxanide furoate B Chloroquine C Metronidazole D Emetine Ans. Although amoebic liver abscess is infrequent in children, the outcomeis muchless favourable than it is in adults. When treated with combined emetinehydrochloride, chloroquine, andaspiration, the prognosis is excellent in adults Wilmot, 1962, this regime being more successful than treatment with a single drug Wilmot, Powell, and Adams, The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine in amoebic liver abscess Treatment of Amebic Liver Abscess, Amoebic Liver Abscess - Ddo you have to stop plaquenil slowly In 1948 Conan 1 reported 6 cases of hepatic amebiasis without abscess of the liver successfully treated with chloroquine. In the same year Murgatroyd and Kent 2 reported the cure of a case of refractory amebic abscess of the liver treated with chloroquine. The success of this treatment, after the failure of emetine, diiodo-hydroxyquinoline diodoquine® and penicillin given systemically and proflavine sulfate used locally, was striking. REFRACTORY AMEBIC ABSCESS OF THE LIVER TREATED WITH CHLOROQUINE. EmetineHydrochloride Chloroquine Treatment Children.. Treatment of liver abscess prospective randomized comparison.. A patient with amebic abscess of the liver was treated with standard doses of metronidazole but remained febrile and pulmonary complications developed. Only after other forms of treatment including aspiration and administration of chloroquine phosphate and emetine hydrochloride did he begin to improve and ultimately to recover. Until Conan 1948 demonstrated the amrebicidal action of chloroquine in the liver, emetine preparations had an unchallenged and specific place in the treatment of amoebic liver abscess. We have shown that chloroquine alone is inferior to emetine hydrochloride and dehydro- emetine Wilmot et al. 1958, Powell, Wilmot et al. 1965, although it may be given in combination with advantage Wilmot et al. 1959, 1963. In treatment of amoebic liver abscess, chloroquine may be used instead of or in addition to other medications in the event of failure of improvement with metronidazole or another nitroimidazole within 5 days or intolerance to metronidazole or a nitroimidazole.