Malaria is a serious but rare disease caused by bites from infected mosquitos. Now the drug is used to treat inflammatory diseases. Chloroquine transfection lipofectamine Side effects from stopping plaquenil Symptoms. Over time, Plaquenil can accumulate in the retina and cause permanent irreversible damage to the center of vision. The classic retinal changes appear as a “bull’s eye” area of discoloration of the central part of the retina. Symptoms of Plaquenil toxicity are similar to other macular problems and may include In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias joint pain, dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Some diseases treated with Plaquenil include: Plaquenil lowers your immune system’s ability to cause inflammation. This type of disease occurs when the body's immune system attacks its own healthy tissue. Plaquenil eye damage symptoms Multimodal Imaging in Plaquenil Toxicity, The Risk of Retinal Toxicity with Plaquenil Generic made by plaquenil manufacturerCataract effective by taking plaquenilCan hydroxychloroquine make you tiredHydroxychloroquine wr walter reedChloroquine malaria dna binding theory This can help control symptoms like rashes, skin and mouth sores and joint pain. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. What Is Plaquenil? - American Academy of Ophthalmology. Plaquenil Side Effects on Your Eyes and Vision. Has anyone experienced plaquenil toxicity with damage to eyes?. While Plaquenil can cause a variety of symptoms, most of them are minor and temporary. The most serious symptom, however, is neither minor nor temporary. Permanent, vision-altering retinal damage has been documented in some long-time users of Plaquenil, but it has been regarded as rare, as long as patients use doses appropriate to their mass. Aug 30, 2011 Unfortunately, the retinal damage from these medications is largely irreversible, so it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. Sign/Symptoms Ocular manifestations of hydroxychloroquine include corneal verticillata and retinal toxicity. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash.