It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Chloroquine myopathy Easy bruising plaquenil I am taking Prevacid, but when my stomach hurt with the Plaquenil it didn't help at all. I did get a baseline exam from my ophthalmologist, so that is a good idea. I did get a baseline exam from my ophthalmologist, so that is a good idea. Hi, I JUst wanted to let you know that Plaquenil, and other lupus meds can be rough on your stomach.so in the beginning than long term. My doctor reccomended that I eat 100 calories at least prior to taking Plaquenil and Naproxen. I was prett nauseous the frist 2 weeks on these meds, but over time it diminished. After just 4 days on Plaquenil, I had severe stomach cramps, no appetite, GERD pain, diarrhea and a migraine. Not sure that the migraine was related but it happened on day 4. After contacting my Rheumatologist, I was told to stop taking the drug. When I asked what other drug I could try, he said nothing -no medicine. Hydroxychloroquine comes as a tablet to take by mouth. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Plaquenil stomach Stomach problems with Plaquenil • Johns Hopkins Arthritis., Plaquenil and stomach issues." Lupus Community. Pros and cons of plaquenilMedicationl plaquenilEffects of ultraviolet ray on chloroquine Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Stomach cramps from Plaquenil - what to do? Lupus Forums.. Plaquenil Hydroxychloroquine for Lupus - LupusCorner. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, Hi honey, YES.stopping plaquenil for a couple of days can cause symptoms to arise or get worse.needs to be taken exactly as prescribed. Twice a day, every day. Missing one dose wont make a major difference but skipping more then one, or days absolutely can. My stomach symptoms were so nasty that I already suspected IBS or even Crohn's or something equally horrible My GP put me on probiotics in May/June because of the symptoms. They helped pretty well without them I wouldn't have been able to go anywhere ever so I continued with them and only stopped them AFTER stopping Plaquenil and realizing my stomach wasn't acting up anymore.