It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil cyst buster Hydroxychloroquine mechanism of action in sle Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. An African American woman, aged 50 years, presents with painless “bruises” on her leg. She first noticed bruises on both legs a year ago and reports that they have since become larger. Aug 14, 2013 Hydroxychloroquine is an antimalarial medication that can cause hyperpigmentation of nails, mucosa, and skin 1–5. Retrospective studies cite the incidence of drug-related hyperpigmentation from hydroxychloroquine to be as high as 33% of individuals. Elder abuse is a cause of significant morbidity and mortality in older individuals 7–9. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil induced bruising on shins Hydroxychloroquine-induced pigmentation in patients with., Painless, bruise-like hyperpigmentation on a woman with. Plaquenil toxicity in macular octHow long chloroquine tablets is good after expiration dateOphthalmologic exam for plaquenil usePlaquenil anti inflammatorySide effects plaquenil 200 mg Most patients had at least one condition that predisposed to easy bruising. The pigmentation was independently associated with oral anticoagulants, antiplatelet agents, and blood hydroxychloroquine concentration. This supports the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. Contaminated Injections RA and Unemployment, Lupus and Bruising, and Rheumatic Fever Pain.. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. Bruising or discoloration, Swelling and Swelling Common.. Erythema nodosum is a skin condition that causes painful swollen red or purple bumps most commonly on the shins. Sometimes the bumps can also form on other parts of the body. WebMD's guide to the symptoms of lupus. When you have lupus, something happens to your body’s natural defense system your immune system to make it work incorrectly. Instead of only targeting. Hydroxychloroquine Plaquenil stimulates the pigment producing cells in the skin called melanocytes. As a result, there is both hemosiderin iron and melanin accumulation in the dermis. The exact reasons why this phenomenon happens is not clear. However, trauma and bruising may faciliate the developement of pigmentation.