Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine off label uses Hydroxychloroquine sulfatelupus With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. As for the vitamins, I noticed they also were really helping w my joints. I was on Plaquenil in the past for joint problems and liked it. I didn't notice any other side effects, but hearing of sight loss scares me as I am looking to go back on them. I think I will be experimenting w MSM a little more before turning to Plaquenil. Hope this is. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. I do go for intense eye examinations every 6 months to see if there is a difference in my eyesight from my base examine. I do have SJS also. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Going off plaquenil What Are The Side Effects Of Stopping Methotrexate?, Lupus, Humor, and Wellness Growing Back that Gorgeous Head of Hair What otc meds can be taken with plaquenilPlaquenil 200 mg indications The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Let me tell you what weaning down from Plaquenil is like.. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. Stopping Plaquenil - General Discussion - Life With Lupus. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. For the four years that I took the drug. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember.