Additionally, another exception occurred while executing the custom error page for the first exception. Applies to chloroquine: oral tablet Along with its needed effects, chloroquine may cause some unwanted effects. Chloroquine generic name Chloroquine dna supercoiling Multifocal ERG has the ability to detect early macular dysfunction, so it should be included as part of baseline screening. A maximum daily dose of Plaquenil of 5.0mg/kg real weight is recommended. Communication with the prescribing physician is also key to proper treatment and management of your patient. Diabetic Maculopathy The macula is the central area of the retina. Diabetic maculopathy is a condition that can result from retinopathy. Diabetic maculopathy is when the macula sustains some form of damage, the part of the eye which provides us with our central vision. It is responsible for sharp vision, such as watching TV or reading. Applies to chloroquine compounding powder, injectable solution, oral tablet. Ocular. Maculopathy and macular degeneration may be irreversible. Irreversible retinal damage has been reported in patients receiving long-term or high-dose 4-aminoquinoline therapy. Retinopathy has been reported as dose related. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Chloroquine maculopathy treatment Hydroxychloroquine-Induced Retinal Toxicity - American., Diabetic Maculopathy Symptoms, Causes & Treatment How To. Chloroquine suicide Window defects in both eyes. A diagnosis of chloroquine-induced bull’s eye maculopathy was made. Following discussion with the patient’s physician, chloroquine treatment was discontinued. Azathioprine was substituted as a treatment for her rheumatoid arthritis and she responded well. On follow-up examination 3 months later, the woman’s vision Chloroquine-induced bull’s eye maculopathy. Chloroquine Side Effects Common, Severe, Long Term -. Maculopathy Causes and Symptoms - Micro Chirurgia Oculare. RUBIN M, BERNSTEIN HN, ZVAIFLER NJ. STUDIES ON THE PHARMACOLOGY OF CHLOROQUINE. RECOMMENDATIONS FOR THE TREATMENT OF CHLOROQUINE RETINOPATHY. Arch Ophthalmol. 1963 Oct. 4-81. Yaylali SA, Sadigov F, Erbil H, Ekinci A, Akcakaya AA. Chloroquine and hydroxychloroquine retinopathy-related risk factors in a Turkish cohort. Plaquenil-induced maculopathy is a form of retinal toxicity that is associated with long-term use of of the anti-inflammatory medication plaquenil. The drug-induced maculopathy is associated with the following risk factors Cumulative dose level of 1,000 grams of plaquenil; Patients with existing retinal or macular disease; Patients over the. Some patients, toxicity may first present as pericentral retinopathy and thus requires screening outside the macula. We assume chloroquine retinopathy follows a similar course as hydroxychloroquine retinopathy and so these guidelines also apply to patients taking chloroquine therapy.