Hydroxychloroquine in chikungunya

Discussion in 'Hydroxychloroquine Plaquenil' started by romodos, 28-Feb-2020.

  1. calibr XenForo Moderator

    Hydroxychloroquine in chikungunya


    Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy.

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    Materials and methods. One hundred and twenty patients diagnosed to have chikungunya arthritis clinically were randomized to one of four groups receiving combinations of aceclofenac 200 mg/day, hydroxychloroquine 400 mg/day and prednisolone 10 mg/day. The chikungunya virus CHIKV infection epidemic has emerged as a significant public health concern in the last 10–15 years, especially in Asian and south American countries. However, with ever-expanding tourism and migration, cases have now been reported in north America and Europe. With a median follow-up time of 21 months a mean of 25 months, MTX led to a positive clinical response in 54 out of 72 patients 75% with 67% in RA, 80% in SA, 100% in UP; 7 cases developed bone destruction while undergoing MTX treatment, whereas recovery was achieved for 6 patients 3 RA and 3 SA.

    Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease.

    Hydroxychloroquine in chikungunya

    Hydroxychloroquine Side Effects, Dosage, Uses, and More, Chikungunya arthritis

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  7. A clinical trial conducted during the chikungunya outbreak in 2006 in Réunion Island showed that oral chloroquine treatment did not improve the course of the acute disease De Lamballerie et al. 2008 and that chronic arthralgia on day 300 post-illness was more frequent in treated patients than in the control group Roques et al. 2018.

    • Of chloroquine and COVID-19 - ScienceDirect.
    • Specific Management of Post-Chikungunya Rheumatic Disorders..
    • Treatment of Chronic Chikungunya Arthritis With Methotrexate..

    Chikungunya virus is spread to people by the bite of an infected mosquito. The most common symptoms of infection are fever and joint pain. Other symptoms may include headache, muscle pain, joint swelling, or rash. Chinese found an In Vitro activity of Plaquenil, and maybe in Vivo too but the live study is not yet published. A Professor in France got interested in doing a trial in Marseille hospital, and was agreed a few days ago to do so Pr Raoult; He is studying Plaquenil use in viral and intracellular. Indian Journal of Rheumatology 2008 September Original Article Volume 3, Number 3; pp. 93–97 Methotrexate and hydroxychloroquine combination therapy in chronic chikungunya arthritis a 16 week study S Pandya ABSTRACT Objective To study the clinical profile of patients of chronic chikungunya arthritis presenting to a rheumatology OPD in the Western part of India and to judge the treatment.

     
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    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Hydroxychloroquine Uses, Dosage & Side Effects - Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil Uses, Dosage & Side Effects -
     
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    UCTD/ starting Plaquenil -
     
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