Artemisinin Combination Therapies, or ACTs, are currently the frontline treatments against malaria. Although these treatments are working well in many parts of the world, there is serious concern that malaria parasites are once again developing widespread resistance to this vital treatment. Plaquenil side effects eyes symptoms Dry skin from plaquenil Plaquenil therapy icd-9 Drug interactions. What are the potential side. effects of chloroquine? Chloroquine is a relatively well-tolerated. medicine. The most common adverse reactions reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking chloroquine with food. Chloroquine may also cause itching in some people. In many places, chloroquine treatment is no longer effective because of drug resistant P. vivax. There is a shortage of accurate diagnostics; What is the WWARN network doing to stop this? Facilitating Study Groups to generate pooled analyses to understand the efficacy and safety of antimalarials, incuding for sub-populations Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Quinine comes from the bark of a tree native to South America. As the threat of antimalarial drug resistance grows, there is increasing pressure to sustain the efficacy of existing treatments, develop alternative treatments, as well putting in place preventative measures such as bednets. Chloroquine drug resistance Chloroquine-Resistant Malaria The Journal of Infectious., Malaria Drug Resistance Worldwide Antimalarial Resistance. Malaria prophylaxis with chloroquine Drug Resistance Resistance of Plasmodium parasites to Chloroquine is widespread see INDICATIONS AND USAGE, Limitations of Use in Malaria and WARNINGS. Plasmodium parasites exhibiting reduced susceptibility to hydroxyChloroquine also show reduced susceptibility to Chloroquine. Chloroquine - Prescription Drug Information.. Chloroquine Oral Uses, Side Effects, Interactions, Pictures, Warnings.. History of antimalarials Medicines for Malaria Venture. Chloroquine is a member of the drug class 4-aminoquinoline. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. Chloroquine Aralen is used for preventing and treating malaria and amebiasis, an infection of the intestines caused by a parasite. Chloroquine mechanism of drug action and resistance in Plasmodium falciparum. Slater AF1. Author information 1Picower Institute for Medical Research, Manhasset, NY 11030. Quinoline-containing drugs such as chloroquine and quinine have had a long and successful history in antimalarial chemotherapy.