After the fevers I get severe chilblains on my fingers, ears and toes. This I have always attributed to the Raynauds I was diagnosed with as a child. Chloroquine primaquine combination Chloroquine phosphate for ich Oct 22, 2019 In 2002 I got a new doctor that diagnosed me with SLE and started me on plaquenil. I don't remember exactly how long it took but after some months the fever went down. I have always had fatigue after my first flare and joints and muscle pain every day along with many respiratory infections and skin rashes. But the fever has stayed away. The bark from the "fever tree' was found to contain the antimalarial compound, quinine. In 1820, chemists purified the quinine from the bark. Fast forward to 1951, when there was anecdotal evidence of improvement in lupus and rheumatoid arthritis by WWII Allied troops who were taking a synthetic form of quinine, called quinacrine, to prevent malaria. But I was just gonna tell you that I was on Plaquenil for quite a while, it was not until I got off for about 4 months that I began to lose chunks of hair. So I did get back on the Plaquenil and got the hair and inflammation lined back out and then I tapered the plaquenil down to 200mg when I was originally on 400. So the reason for the post is to know if anyone here has had similar issues with unexplained fevers that cause chilblains? They typically form in the evenings and hurt like hell. It very mild case that is actually more sensitive to heat then cold. When i went off plaquenil i got fevers Plaquenil question -, Taking Plaquenil for Rheumatoid Arthritis Ocular side effects from plaquenilCipro and plaquenilPlaquenil treatment sle Plaquenil comes in 200 milligram mg tablets that are taken by mouth. To prevent malaria in adults, two tablets are typically taken once a week, on the same day each week. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hair loss and Plaquenil? DailyStrength. Lupus Symptoms Fatigue, Fever, Swollen Lymph Nodes, Rash, & More. I was even thinking of trying it again to see if the rash was just a one-off thing, but after doing some research I found a study about patients' allergic reactions to Plaquenil and the pictures looked exactly like my rash. Also read that allergic reactions can get even worse when triggered again, so I won't be trying anymore. Aug 29, 2014 One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. Jan 11, 2012 So that's the update. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Take it from me! I am feeling much better after bumping my dose back up over the last few.