Keep in mind that most people with Sjogren's stay healthy and don't have serious problems. You should be able to keep doing all the things you love to do without making many changes. Number needed to treat hydroxychloroquine Chloroquine hydrochloride tablets I was on HCQ 400 daily for one week and experienced buzzing lips, sharp-stop me in my tracks-heart pain, severbloat/cramps, worse neuropathy. "The Lupus Book" has suggested the brand name Plaquenil is better for some people. It's terrible no studies have been done. My rheumatologist stated there is no significant difference. Chapped lips is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Methotrexate, and have Birth control. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Sjögren’s syndrome, which causes dry eyes and dry mouth. Plaquenil lowers your immune system’s ability to cause inflammation. This can help control symptoms like rashes, skin and mouth sores and joint pain. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. Conditions like this are called autoimmune diseases. Sjogren's causes your immune system to go haywire and attack healthy cells instead of invading bacteria or viruses. Plaquenil and dry lips Plaquenil and dry mouth and eyes - Sjogren's World, Will you have Chapped lips with Plaquenil - eHealthMe How to reduce stomach discomfort with plaquenilHow long should you take hydroxychloroquineWhy would you take hydroxychloroquine and mycophenolateIs plaquenil an nsaid drug The thing is I have not been diagnosed with Sjogren's yet. As I understand taking Plaquenil and seeing if it helps are a part of diagnosis. What makes me unwilling to take the risk, however small it may be, is that I only seem to have two symptoms of Sjogren's dry eyes and Raynaud's phenomenon. I've never noticed any mouth dryness myself. Dry eyes, Sjogren’s and Plaquenil.. What Is Plaquenil? - American Academy of Ophthalmology. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. These machines also can help your dry mouth or nose. Also for dry nose, try a nasal saline spray or gel. If dry skin is a problem, use warm water, not hot, when you bathe or shower. Instead of. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Specifically, anti-malarial medications have shown to improve muscle and. But many times I also get dry mouth along with it. Now I wonder if I might have Sjogren's only because last summer I sudden eye problems and was diagnosed with dry eye syndrome. And my eye problems come in flares, like all my other problems. My opthalmologist did tell me that dry eye syndrome is commonly found in people with lupus.